- Recommended name
- 11-nor-tetrodotoxin-6-ol
- Synonyms
- n/a
- Recommended acronym
- 11-nor-TTX-6-ol
- Abbreviation
Progenitors
No progenitors registered
Vector Species
No vector species registered
- Structure
- Formula
- n/a
- Exact mono-isotopic mass
- n/a
- Molfile
- n/a
- Alternative molfiles
- n/a
- SMILES
- Alternative SMILES
- n/a
- InChi key
- Alternative InChi keys
- n/a
- InChi
- Alternative InChis
- Spectra available
- Unknown
- Chem files
References
- Maehara et al, 2017
- Total Synthesis of (−)-Tetrodotoxin and 11-norTTX-6(R)-ol Tomoaki Maehara, Dr. Keisuke Motoyama, Dr. Tatsuya Toma, Dr. Satoshi Yokoshima, Prof. Tohru Fukuyama 11 January 2017 https://doi.org/10.1002/anie.201611574
- Certified
- False
- Certified links
-
-
n/a
- Non certified reference material
- False
Chemical analysis
- Research
- Unknown
- Standardized
- False
- Validated
- False
- Official
- n/a
Structure recognition assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Functional assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Animal assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
- Regulatory status
- False
- Human toxic syndrome(s)
- n/a
- Organ system toxicity
- n/a
- Risk assessment
- Unknown
- Molecular targets known
- Unknown
- Molecular targets
- n/a
- Toxic to aquatic animals
- Unknown
- TEF available
- False
TEF References
- Yotsu et al, 2014
- • 54 μg/kg b.w. for 11-nor-TTX–6(S)-ol (Yotsu et al., 2014)
- Endo et al, 1988
- • 70 μg/kg b.w. for 11-nor-TTX–6(R)-ol (Endo et al., 1988). Endoa A., Khora S.S., Murata M., Naoki H., Yasumoto T. Isolation of 11-nortetrodotoxin-6(R)-OL and other tetrodotoxin derivatives from the puffer Fugu niphobles. Tetrahedron Lett. 1988;29:4127–4128. doi: 10.1016/S0040-4039(00)80434-7.
- Notes
- Relative toxicity to mice ip noted, but TEF not formally defined • 54 μg/kg b.w. for 11-nor-TTX–6(S)-ol (Yotsu et al., 2014) • 70 μg/kg b.w. for 11-nor-TTX–6(R)-ol (Endo et al., 1988).